Sickle Cell Trait Research Paper Example | Topics and Well Written Essays - 1250 words

Sickle Cell character - Research Paper ExampleNormal red job prison cells are smooth and round and wherefore can easily move through blood vessels. Sickle cell property (AS) differs from sickle cell distemper (SS) in which two abnormal hemoglobin genes is present, one from each parent. Sickle cell disease is a genetic disorder that affects red blood cells, making them rigid, sticky and sickle shaped. Sickling causes plugging of blood vessels to cash in ones chips which essentially hinders the transport of oxygen from lungs to dissimilar organs in the body. The objective of this paper is to highlight the various aspects of the sickle cell trait namely the historical evidences, mode of inheritance and its various complications. Historical evidences The introductory case of death due to sickle cell trait was documented between March 1968 and February 1969 at Fort Bliss where four army recruits collapsed and died during basic training. Since 2000, nine college football players have died from sickle cell trait complications, by far the biggest non-traumatic killer in the sport. In March 2008, a jury finds the UCF variation Association negligent in the death of 19-year old Erech Plancher, who collapsed and died after offseason conditioning drills. ... When both parents have the trait, their tike will have a 50% chance of having the trait (hemoglobin AS), as well as a 25% chance of being normal (hemoglobin AA) and a 25% chance of having sickle cell disease (hemoglobin SS). These risks are associated with each pregnancy. Linus Pauling asserts I have suggested that the time might come in the future when selective information about heterozygosity in such serious genes as the sickle cell anemia gene would be tattooed on the forehead of the carriers, so that young men and women would at once be warned not to root in love with each other. Complications Sickle cell trait is normally considered a harmless condition, yet extreme physical activity can lead to co mplications that can be fatal. Complications from sickle cell trait are important because about three million people in the United States have this genotype, about 40 to 50 times the number with sickle cell disease. (Kark 2000). When the individual is at rest, their red blood cells are normal but rigorous exercise regimes induce sickling to occur and cause several problems. such(prenominal) problems include increased urinary tract infection in women, gross hematuria, splenic infarction with superlative hypoxia or exercise, and life-threatening complications of exercise, exertional heat illness (exertional rhabdomyolysis, heat stroke, or renal failure) or idiopathic fast death (Sears 1978 Serjeant 1992 Kark and Ward 1994 and Sears 1994). We will consider each of these problems in more detail. The frequency of urinary tract infection is higher in women with SCT than in racially matched controls, especially during pregnancy, when the frequency is about doubling (Pastore, Savitz and Thorp 1990). The presence of SCT in men was not associated with